The man/machine interface in information retrieval: Providing access to the casual user

This study is concerned with the difficulties encountered by casual users wishing to employ Information Storage and Retrieval Systems. A casual user is defined as a professional who has neither time nor desire to pursue in depth the study of the numerous and varied retrieval systems. His needs for on-line search are only occasional, and not limited to any particular system. The paper takes a close look at the state of the art of research concerned with aiding casual users of Information Storage and Retrieval Systems. Current experiments such as LEXIS, CONIT, IIDA, CITE, and CCL are presented and discussed. Comments and proposals are offered, specifically in the areas of training, learning and cost as experienced by the casual user. An extensive bibliography of recent works on the subject follows the text

A report on the USL NASA/RECON project. Part 1: The development of a transportable, university level, IS and R educational program

A project is described which has as its goal the production of a set of system-independent, discipline-independent, transportable college level courses to educate science and engineering students in the use of large-scale information storage and retrieval systems. This project is being conducted with the cooperation and sponsorship of NASA by R and D teams at the University of Southwest Louisiana and Southern University. Chapter 1 is an introduction, providing an overview and a listing of the management phases. Chapter 2 furnishes general information regarding accomplishments in areas under development. Chapter 3 deals with the development of the course materials by presenting a series of diagrams and keys to depict the progress and interrelationships of various tasks and sub-tasks. Chapter 4 presents plans for activities to be conducted to complete and deliver course materials. The final chapter is a summary of project objectives, methods, plans, and accomplishments

IBM PC/IX operating system evaluation plan

An evaluation plan for the IBM PC/IX Operating System designed for IBM PC/XT computers is discussed. The evaluation plan covers the areas of performance measurement and evaluation, software facilities available, man-machine interface considerations, networking, and the suitability of PC/IX as a development environment within the University of Southwestern Louisiana NASA PC Research and Development project. In order to compare and evaluate the PC/IX system, comparisons with other available UNIX-based systems are also included

Within-host dynamics of the emergence of tomato yellow leaf curl virus recombinants

Tomato yellow leaf curl virus (TYLCV) is a highly damaging begomovirus native to the Middle East. TYLCV has recently spread worldwide, recombining with other begomoviruses. Recent analysis of mixed infections between TYLCV and Tomato leaf curl Comoros begomovirus (ToLCKMV) has shown that, although natural selection preserves certain co-evolved intra-genomic interactions, numerous and diverse recombinants are produced at 120 days post-inoculation (dpi), and recombinant populations from different tomato plants are very divergent. Here, we investigate the population dynamics that lead to such patterns in tomato plants co-infected with TYLCV and ToLCKMV either by agro-inoculation or using the natural whitefly vector Bemisia tabaci . We monitored the frequency of parental and recombinant genotypes independently in 35 plants between 18 and 330 dpi and identified 177 recombinants isolated at different times. Recombinants were detected from 18 dpi and their frequency increased over time to reach about 50% at 150 dpi regardless of the inoculation method. The distribution of breakpoints detected on 96 fully sequenced recombinants was consistent with a continuous generation of new recombinants as well as random and deterministic effects in their maintenance. A severe population bottleneck of around 10 genomes was estimated during early systemic infection-a phenomenon that could account partially for the heterogeneity in recombinant patterns observed among plants. The detection of the same recombinant genome in six of the thirteen plants analysed beyond 30 dpi supported the influence of selection on observed recombination patterns. Moreover, a highly virulent recombinant genotype dominating virus populations within one plant has, apparently, the potential to be maintained in the natural population according to its infectivity, within-host accumulation, and transmission efficiency - all of which were similar or intermediate to those of the parent genotypes. Our results anticipate the outcomes of natural encounters between TYLCV and ToLCKMV

The Fermi motion contribution to J/\psi production at the hadron colliders

We investigate the relativistic Fermi motion effect in the case of $J/\psi$ production in various hadron colliders. A light-cone wave function is adopted to represent the $J/\psi$ final state. The change in the confinement parameter which sets a scale for the size of the final state, allows one to see the effect in an explicit manner. While the effect has considerable influence on the fragmentation probabilities and the differential cross sections, the total cross sections are essentially left unchanged. such a feature is in agreement with the momentum sum rule which the fragmentation functions should satisfy.Comment: 10 pages, 4 figures, to appear in Phys. Lett.

USL NASA/RECON project presentations at the 1985 ACM Computer Science Conference: Abstracts and visuals

This Working Paper Series entry represents the abstracts and visuals associated with presentations delivered by six USL NASA/RECON research team members at the above named conference. The presentations highlight various aspects of NASA contract activities pursued by the participants as they relate to individual research projects. The titles of the six presentations are as follows: (1) The Specification and Design of a Distributed Workstation; (2) An Innovative, Multidisciplinary Educational Program in Interactive Information Storage and Retrieval; (3) Critical Comparative Analysis of the Major Commercial IS and R Systems; (4) Design Criteria for a PC-Based Common User Interface to Remote Information Systems; (5) The Design of an Object-Oriented Graphics Interface; and (6) Knowledge-Based Information Retrieval: Techniques and Applications

Fucosidases from the human gut symbiont Ruminococcus gnavus

The availability and repartition of fucosylated glycans within the gastrointestinal tract contributes to the adaptation of gut bacteria species to ecological niches. To access this source of nutrients, gut bacteria encode α-L-fucosidases (fucosidases) which catalyze the hydrolysis of terminal α-L-fucosidic linkages. We determined the substrate and linkage specificities of fucosidases from the human gut symbiont Ruminococcus gnavus. Sequence similarity network identified strain-specific fucosidases in R. gnavus ATCC 29149 and E1 strains that were further validated enzymatically against a range of defined oligosaccharides and glycoconjugates. Using a combination of glycan microarrays, mass spectrometry, isothermal titration calorimetry, crystallographic and saturation transfer difference NMR approaches, we identified a fucosidase with the capacity to recognize sialic acid-terminated fucosylated glycans (sialyl Lewis X/A epitopes) and hydrolyze α1-3/4 fucosyl linkages in these substrates without the need to remove sialic acid. Molecular dynamics simulation and docking showed that 3'-Sialyl Lewis X (sLeX) could be accommodated within the binding site of the enzyme. This specificity may contribute to the adaptation of R. gnavus strains to the infant and adult gut and has potential applications in diagnostic glycomic assays for diabetes and certain cancers